News

2014-2015 Annual Report

May 06, 2015 at 5:14 AM

External Funding & Patents:

Loehrer P (PI). “AMPATH-Oncology Institute: HPV and Cervical Cancer in Kenyan Women with HIV/AIDS”.  Funded by NIH/NCI: U54CA190151. September, 2014 – August, 2019. [Brown DA, Project PI; Ermel A, Co-Investigator]. Total Direct Costs - $594,498.

Zimet, Sturm, Gilkey, Brewer. "Physician-Patient Discourse about HPV Vaccination". Investigator-initiated proposal to Merck & Co., Inc. Total Direct Costs - $39,000.

Zimet G & Downs S (Co-PIs). “Use of a Patient Education/Messaging Platform to Increase Uptake and Series Completion of HPV Vaccine”. Funded by the Merck-Regenstrief Program in Personalized Health Care Research and Innovation (Project 20). February, 2015 – January, 2016. [Co-Investigators include Center for HPV Research faculty Wanzhu Tu]. Total Direct Costs - $286,674.

Zimet G & Downs S (Co-PIs). “HPV Vaccination: Evaluation of Reminder Prompts for Doses 2 & 3”. Funded by the Merck-Regenstrief Program in Personalized Health Care Research and Innovation (Project 21). February, 2015 – January, 2016. [Co-Investigators include Center for HPV Research faculty Wanzhu Tu]. Total Direct Costs - $196,287.

Meyerson, Comer, Zimet. “Cervical Cancer Policy Communication Dashboard”. Investigator-initiated proposal funded by Roche Diagnostics Corporation. May, 2015 – December, 2016. Total Direct Costs - $80,000.

Meyerson, Comer, Zimet. “Cervical Cancer Policy Communication Dashboard”. Investigator-initiated proposal funded by the Anita Aldrich Foundation. May, 2015 – April, 2016. Total Direct Costs - $30,000.

 

Internal Funding:

Androphy E & Davisson VJ. “"Drug-like inhibitors of HPV-16 E6”. Indiana CTSI Collaboration in Translational Research grant award.

 

Funding pending:

Meyerson et al. “Cervical Cancer Screening on the STD FastTrack” – NIH R15 Submitted 10/2014.

Fontenot, Zimet, Mayer, Rosenberger, Stupiansky. "Using Mobile Application Strategies to Increase HPV Vaccination Rates among Young MSM" – NIH R21 Submitted 03/2015.

E. Androphy and V.J. Davisson. “Mutational and physical analysis of the binding interface between HPV E6 and E6AP” - NIH R21 AI111116-01A1 submitted 7/16/14.

Woodall, Zimet et al. “Smartphone Technology for Boys and Parents: Improving HPV Vaccine Uptake” – NIH R01 Submitted 02/15.

Vadaparampil, Zimet, Fontenot, Shew, Giuliano. “Assessing Patterns of Physician Recommendations, Obstacles, Attitudes, and Communication regarding HPV Vaccination: Influence of New Guidelines (APPROACHING)” – NIH R01 Submitted 04/2015.

 

Papers "in press" as of March 31, 2015

Rickert VI, Auslander BA, Cox DS, Rosenthal SL, Rupp RE, Zimet GD. School-based HPV immunization of young adolescents: Effects of two brief health interventions. Hum Vacc Immunother (in press).

 

Papers Published - 7/1/2013 - 6/30/2014

1.   van den Berg JJ, Larson HE, Zimet GD, Lally MA. Feasibility of bundling human papillomavirus vaccination, rapid human immunodeficiency virus testing, and personalized risk reduction counseling for young gay and bisexual men. LGBT Health 2014;1(3):233-237.

2.   Paul P, Tanner A, Gravitt P, Vijayaraghavan K, Shah K, Zimet G, CATCH Study Group. Acceptability of HPV vaccine implementation among parents in India. Health Care Women Int 2014;35(10):1148-1161.

3.   Malo TL, Giuliano AR, Kahn JA, Zimet GD, Lee J-H, Zhao X, Vadaparampil ST. Physicians’ human papillomavirus recommendations in the context of permissive guidelines for male patients: A national study. Cancer Epidemiology, Biomarkers & Prevention 2014;23(10):2126-2135. PMCID:PMC4184998 [Available on 2015/10/1].

4.   Taylor JL, Zimet GD, Donahue K, Alexander AB, Shew ML, Stupiansky NW. Vaccinating sons against HPV: Results from a U.S. national study of parents. PLoS One 2014; 9(12):e115154. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0115154. PMCID: PMC4277268

5.   Anderson TA, Schick V, Herbenick D, Dodge B, Fortenberry JD. Human Papillomavirus on Vaginally Inserted Sex Toys Before and After Cleaning among Women who have Sex with Women and Men. Sex Transm Infect 2014;90(7):529-531.

6.   Cox, DS, Sturm, L A., Cox, AD. Effectiveness of Asking Anticipated Regret in Increasing HPV Vaccination Intention in Mothers,” Health Psychology 2014;33(9):1074-1083.

7.  Zimet GD. Health care professionals and adolescent vaccination: A call for intervention research. Hum Vaccin Immunother 2014;10(9):2629-2630.

8. Rickert V, Rehn SJ, Aalsma MC, Zimet GD. The role of parental attitudes and provider discussions in uptake of adolescent vaccines. Vaccine 2015;33:642-647.

9. Meyerson B, Sayegh MA, Davis A, Arno J, Zimet GD, LeMonte AM, Williams JA, Barclay L, Van Der Pol B. Cervical cancer screening in an STD clinic? Adoption experiences from a Midwestern clinic. Am J Public Health 2015;105 Suppl 2:e8-e14.

10. Kanginakudru S, DeSmet M, Thomas Y, Morgan IM, Androphy EJ. Levels of the E2 interacting protein TopBP1 modulate papillomavirus maintenance stage replication. Virology 2015;478:135-142.

11. Ermel A, Ramogola-Masire D, Zetola N, Tong Y, Qadadri B, Azar MM, Brown DR. Invasive cervical cancers from women living in the United States or Botswana: Differences in human papillomavirus type distribution. Infect Agent Cancer 2014;9:22.

 

Organization of conferences, symposia, workshops etc.

Midwest AIDS Training & Education Center Meeting – 2015 HIV/AIDS Update: Advances in Care & Prevention. May 15, 2015.  Meeting co-sponsored by the IUPUI Center for HPV Research.

Joel Palefsky (Center-Sponsored Keynote):

 

Gregory Zimet and Zeev Rosberger, chairs, Satellite Symposium Session: "The Invisible Man in HPV, Part 4: Making Progress". Conducted at the 29th International Papillomavirus Conference, Seattle, WA, August 24, 2014.

 

HPV-Related Scientific Research Presentations (July 1, 2014 – 2015)

1. Best C, Alexander AB, Stupiansky NW, Zimet GD. How health care providers make decisions about male HPV vaccination: Variability in the face of ACIP guidelines. Presented at the 29th International Papillomavirus Conference, August, 2014, Seattle, WA.

2. Donahue K, Stupiansky N, Cox A, Cox D, Zimet G. Effects of a brief health messaging intervention on HPV vaccine acceptability among parents of adolescent sons. To be presented at the 29th International Papillomavirus Conference, August, 2014, Seattle, WA.

3. Zimet GD, Auslander BA, Cox DS, Rosenthal SL, Rupp RE, Rickert VI. Health messaging intervention for HPV vaccination in school-based health centers: Changing intentions but not uptake. Presented at the 29th International Papillomavirus Conference, August, 2014, Seattle, WA.

4. Breitkopf CR, Ipp LS, De Roche A, Ebel SC, Zimet G, Catallozzi M, Rosenthal SL. Perceptions and predictors of New York City adolescents’ responsibility in HPV vaccine series completion. Presented at the 29th International Papillomavirus Conference, August, 2014, Seattle, WA.

5. Kasting ML, Cummings T, Zimet GD, Rosenberger JG, Stupiansky NW. Lack of knowledge has consequences: HPV vaccination among young MSM. Presented at the 29th International Papillomavirus Conference, August, 2014, Seattle, WA.

6. Heffernan ME, Daley EM, Zimet GD. Health promotion lessons from the gendered implementation of the HPV vaccine programs for girls and its disadvantages for cross-cultural populations. Presented at the 29th International Papillomavirus Conference, August, 2014, Seattle, WA.

7. Ermel A, Yan T, Shew M, Tu W, Brown D. HPV types 6 and 18 antibodies are associated with lack of subsequent type-specific HPV DNA detection in unvaccinated adolescent women. Presented at the 29th International Papillomavirus Conference, August, 2014, Seattle, WA.

8. Marcias Parra M, Gutierrez M, Restrepo J, Ucros S, Herrera T, De Valle O, Engle E, Huicho L, Christensen S, Julien K, Shew M, Maansson R, Caldwell N, Luxembourg A, Sobanjo-ter Meulen A. Immunogenicity and tolerability of a 9-valent HPV vaccine given concomitantly with Menactra and Adacel in 11 to 15 year old boys & girls. Presented at the 29th International Papillomavirus Conference, August, 2014, Seattle, WA.

9. Shew M, Kester L, Tong Y, Ermel A, Fortenberry JD, Tu W, Brown D. Sexually transmitted infections and behaviors: Association with HPV serological response in adolescent women. Presented at the 29th International Papillomavirus Conference, August, 2014, Seattle, WA.

10. Shew M, Tong Y, Tu W, Ermel A, Brown D. Chlamydia infection and unprotected sex increases risk of 37 types of HPV redetection. Presented at the 29th International Papillomavirus Conference, August, 2014, Seattle, WA.

11. Anderson T, Donahue K, Weaver B, Fortenberry JD. A prospective study of digital transmission of HPV. Presented at the 29th International Papillomavirus Conference, August, 2014, Seattle, WA.

12. Rietz A, Androphy E. Identification and characterization of HPV-16 E6 inhibitors. Presented at the 29th International Papillomavirus Conference, August, 2014, Seattle, WA.

13. Ermel A, Ramogola-Masire D, Zetola N, Tong Y, Qadadri B, Azar M, Brown D. Invasive cervical cancers from women living in the United States or Botswana: Differences in human papillomavirus type distribution. Presented at the 29th International Papillomavirus Conference, August, 2014, Seattle, WA.

14. Ermel A, Macharia B, Oran’o O, Qadadri B, Tong Y, Brown D. Invasive cervical cancers from women living in the United States or Kenya: HPV type distribution. Presented at the 29th International Papillomavirus Conference, August, 2014, Seattle, WA.

15. Saah A, Luxembourg A, Brown D. Addressing an unmet need using a 9-valent virus-like particle (VLP)-Based HPV vaccine. Presented at the 29th International Papillomavirus Conference, August, 2014, Seattle, WA.

16. Skinner SR, Cooper S, Davies C, Stoney T, Marshall H, Collins J, Parella A, Jones J, Hutton H, McGeechan K, Zimet G, Kaldor J, Regan D, Whyte P, Leask J, Kang M, Brotherton J, Richmond P, McCaffery K, Garland S, Braunack-Mayer A. Improving school based HPV vaccination delivery: The HPV.edu study. Presented at the PCC2015 Conference, February 22, 2015, Melbourne, Australia.

17. Donahue K, Hendrix K, Sturm L, Zimet G. Ahead of the curve: What predicts HPV vaccine initiation among nine- and ten-year olds? Presented at the meeting of the Society for Adolescent Health and Medicine, March, 2015, Los Angeles, CA.

18. Auslander BA, Meers JM, Short MB, Zimet GD, Rupp RE, Rosenthal SL. Reasons for the Gap between Parental Intentions and Initiation of HPV vaccination. To be presented at the 18th Annual NFID Conference on Vaccine Research, April 13-15, 2015, Bethesda, MD.

 

New collaborators

Peter Szilagyi, UCLA

Susan Vadaparampil, Moffitt Cancer Center

Gill Woodall, University of New Mexico

Zeev Rosberger, McGill University