Food Allergy Research & Education (FARE) Clinical Network/ FARE Center of Clinical Excellence We are one of a select number of sites across the country with this designation. This gives us access to clinical trials and innovative new research for the treatment of food allergies. Collaborating with the FARE Clinical Network also provides access to the latest evidence-based, advanced treatments and standards for pediatric food allergies.
Food allergy research programs. Our allergists are actively involved in research for emerging treatments for food allergy, to potentially include both oral and "patch" (transcutaneous) immunotherapy. We also monitor outcomes of Food Challenges and have published and presented these studies at national meetings.
Peanut/ Food allergy registry. We house one of the largest registries of children with peanut allergy. This database enables us to detect trends and patterns among children with peanut allergy, which could lead to new opportunities for treatment. We invite all patients with peanut allergy to join this registry. We are now establishing an overall food allergy registry.
Airway microbiome and Airway Inflammation: Dr Kirsten Kloepfer is pursuing a longitudinal study, following a group of neonates recruited at birth. To study the relationship between the upper airway microbiome and both airway inflammation and airway function, she is using: 1) advanced methods for bacterial detection (16S rRNA sequencing); 2) cytokine analysis to measure cellular proteins linked with inflammation; and 3) infant airway function testing. Dr Kloepfer received the AAAAI Faculty Development Award in 2017.
Basic science research programs at the Wells Center The overall goal of this research program is to understand the initiation, pathogenesis and progression of these allergic diseases in the hopes of identifying better ways to treat or prevent allergic symptoms. Research spans many areas from examining the regulation of genes important for the development of T cells involved in allergic inflammation, to the biology of cytokines and other factors that promote allergic disease, to examining lung development and function and how changes contribute to lung reactivity to allergens. Research involves animal models of allergic inflammation, clinical trials, and review of patient databases.
Pollen Count Research: Dr Leickly counts pollens using a Rotorod pollen counter, and publishes them daily on his personal webpage. This data has fueled research comparing local and longitudinal pollen counts that have been published and presented nationally.