Kristen Nichols, PharmD

Kristen Nichols, PharmD

Assistant Professor of Pharmacy Practice, Butler University College of Pharmacy and Health Sciences
Infectious Diseases and Antimicrobial Stewardship Clinical Pharmacist, Riley Hospital for Children at IU Health

Adjunct Assistant Professor of Clinical Pediatrics

Phone: 317-948-4239
Email: knichol4@iuhealth.org
705 Riley Hospital Drive
SFT Room W6111 – Dept of Pharmacy
Indianapolis, IN 46205


Pediatric Infectious Diseases Pharmacy


Dr. Nichols is very interested in promoting the judicious and optimal use of anti-infectives in both inpatient and ambulatory pediatrics, in optimizing antibiotic doses based on pharmacokinetic and pharmacodynamic properties, and in educating pharmacy and medical students and residents.

Dr. Nichols obtained her PharmD at Butler University College of Pharmacy and Health Sciences in 2009. After graduation, she completed a PGY1 Pharmacy Residency at Indiana University Health (formerly Clarian Health) and a PGY2 Pediatric Pharmacy Residency at Riley Hospital for Children.

Following completion of residency, Dr. Nichols began her career as an assistant professor at Butler University. At Butler, she teaches in various didactic and experiential settings with a focus in pediatrics. Her position is co-funded with Riley Hospital for Children, where she is the co-director of the Pediatric Antimicrobial Stewardship Program and where she provides pharmacy services for the Pediatric Infectious Diseases Service. Dr. Nichols is also a founder of the Indiana Coalition for Responsible Antibiotic Use and serves on the Antibiotic Resistance Advisory Committee at the Indiana State Department of Health.


2009 Doctor of Pharmacy, Butler University College of Pharmacy and Health Sciences


  • Scholarship of Teaching Award, Pediatric Pharmacy Advocacy Group 24th Annual Meeting, Minneapolis MN, May 2015
  • Spirit of PPAG Award, Pediatric Pharmacy Advocacy Group 22nd Annual Meeting, Indianapolis IN, May 2013
  • The Christensen Memorial Young Investigator Award, Pediatric Pharmacy Advocacy Group 21st Annual Meeting, Houston TX, April 2012


Riley Hospital for Children at IU Health


Dr. Nichols’ research is primarily focused on topics pertinent to pediatric antimicrobial stewardship with a focus on optimizing antibiotic dosing.  Much of her focus has been in extended- and continuous-infusion beta-lactams in children and in antimicrobial usage and adverse effects.


Molloy L, Nichols K. Infectious diseases pharmacotherapy for children with cystic fibrosis. J Ped Health Care. 2015;29(6):565-578.

Teibel HM, Knoderer CA, Nichols KR. Compatibility of vancomycin and oxacillin during simulated Y-site delivery. Hosp Pharm. 2015;50(8):710-713.

Knoderer CA, Gritzman AL, Nichols KR, Wilson AC. Late-occurring vancomycin-associated acute kidney injury in children receiving prolonged therapy. Ann Pharmacother 2015; 49(10):1113-1119.

Nichols KR, Knoderer CA, Jackson NG, Manaloor JJ, Christenson JC. Success with extended-infusion meropenem after recurrence of baclofen pump-related Achromobacter xylosoxidans meningitis in an adolescent. J Pharm Pract. 2015;28(4):430-3.

Ifeachor AP, Nichols KR, Morris JL, Cox EG, Smith JL, Sinclair EA. Antimicrobial prophylaxis for external ventricular drains in pediatric neurosurgical patients. Paediatr Drugs. 2015; 17(3):239-44.

Jones SJ, Nichols KR, DeYoung HL, Cox EG, Knoderer CA. Linezolid-associated thrombocytopenia in children with renal impairment. J Ped Infect Dis. 2015;4(3):272-275.

Brown KE, Knoderer CA, Nichols KR, Crumby AS. Acid suppressing agents and risk for Clostridium difficile infection in pediatric patients. Clin Pediatr. 2015; Feb 2. [Epub ahead of print]. PMID: 25644650.

Nichols KR, Karmire LC, Cox EG, Kays MB, Knoderer CA. Implementing extended-infusion cefepime as standard of care in a children’s hospital: a prospective descriptive study. Ann Pharmacother. 2015;49(4):419-426.

Knoderer CA, Nichols KR, Cox EG. Optimized antimicrobial dosing strategies: a survey of pediatric hospitals. Paediatr Drugs. 2014;16(6):523-529.

Nichols KR, Knoderer CA, Johnston B, Wilson AC. Cinacalcet administration by gastrostomy tube in a child receiving peritoneal dialysis. J Pediatr Pharmacol Ther. 2014;19(3):202-205.

Knoderer CA, Nichols KR, Lyon KC, Veverka MM, Wilson AC. Are elevated vancomycin serum trough concentrations achieved within the first 7 days of therapy associated with acute kidney injury in children? J Ped Infect Dis. 2014;3(2):127-131.

Webber EC, Cox EG, Smith SS, Warhurst H, Crumby AS, Nichols KR. Conversion of a single-facility pediatric antimicrobial stewardship program to multi-facility application with computerized provider order entry and clinical decision support. Applied Clinical Informatics. 2013;4(4):556-568.

Nichols KR, Edison KM, Rosenbaum MD, Knoderer CA. Vancomycin and gentamicin pharmacokinetic alterations in an adolescent amputee. J Pediatr Pharmacol Ther. 2013;18(1):63-6.

Nichols KR, DeMarco MW, Vertin MD, Knoderer CA. Y-site compatibility of vancomycin and piperacillin/tazobactam at commonly utilized pediatric concentrations. Hosp Pharm. 2013; 48(1):1-4.

Nichols KR, Knoderer CA, Cox EG, Kays MB. System-wide implementation of the use of an extended-infusion piperacillin/tazobactam dosing strategy: feasibility of utilization from a children’s hospital perspective. Clin Ther. 2012;34(6):1459-1465.

Nichols KR, Brown DM, Knoderer CA, Andreoli SP. Cefepime neurotoxicity in an adolescent cystic fibrosis patient with aminoglycoside induced acute kidney injury. J Pharm Technol. 2011;27:164-7.