Faculty

Rachel Vreeman, MD, MS

Rachel Vreeman, MD, MS

Associate Professor of Pediatrics

Phone: 317-278-0552
Email: rvreeman@iu.edu
Children’s Health Services Research
410 W. 10th Street, HITS Suite 1000,
Indianapolis, IN 46202

SPECIALTY

Dr. Vreeman specializes in the long-term care of children and adolescents with HIV in resource-limited settings.

AREAS OF INTEREST

Global Health, pediatric HIV, medication adherence, HIV disclosure, HIV-related stigma, pediatric drug formulations.

Dr. Vreeman is an Associate Professor of Pediatrics at the Indiana University School of Medicine and Director of Research for the Indiana University Center for Global Health. She is also the North American Director of Research for the AMPATH Research Network in Kenya, which provides comprehensive HIV treatment for over 150,000 patients in Kenya. Dr. Vreeman chairs the Pediatric Working Group for the global IeDEA (International Epidemiologic Databases Evaluating AIDS) consortium, a global consortium of HIV care programs.

Dr. Vreeman’s research focuses on improving the provision of healthcare to children within resource-limited settings, focusing on supporting children’s adherence to HIV therapy, disclosure of HIV status, and other HIV-related health behavioral challenges for children and adolescents in sub-Saharan Africa.

EDUCATION

1994-1998 BA English, Cornell University
1998-2002 MD Medicine, Michigan State University - College of Human Medicine
2006-2008 MS Clinical Research Science, Indiana University - School of Medicine
2002-2006 Pediatrics Residency and Chief Residency, IUSM
2006-2008 Fellowship in Children's Health Services Research, IUSM

HONORS & AWARDS

  • 2013-2015 - Watanabe Translational Research Scholar, Indiana CTSI
  • 2013 - Early Career Achievement Award, Indiana University School of Medicine Alumni Association
  • 2012 - NIH Loan Repayment Program “Success Story”
  • 2007-2009 - NIH Loan Repayment Program Award for Pediatric Scientists
  • 2008, AAMC Early Career Women Faculty Professional Development
  • 2008-2009, Indiana CTSI Career Development Award (KL2) 
  • 2009-2010, Indiana CTSI Career Development Award (KL2)
  • 2009-2014, NIH Career Development Award (K23)
  • 2006-2008, Morris Green Pediatric Scientist Scholarship
  • 2006, 2004, Indiana University Pediatric Scholars Award
  • 2005, Ann E. Dyson Child Advocacy Award
  • 2002, Alpha Omega Alpha Honors Society, Michigan State University College of Human Medicine
  • 1998, Summa Cum Laude, Cornell University
  • 1998, Class of 1916 Award for Most Outstanding Honors Thesis, Cornell University
  • 1996-1998, Cornell Tradition Fellow
  • 1994, National Merit Scholar

CLINICAL

Academic Model Providing Access to Healthcare (AMPATH), Western Kenya


RESEARCH & GRANTS

Dr. Vreeman conducts an extensive qualitative and quantitative research program in East Africa that centers on the factors impacting children’s long-term HIV treatment in resource-limited settings, including ART adherence and child HIV disclosure.

She has research experience at the intersection of the global treatment of pediatric HIV infection and health behaviors. She completed a K23 career development award from NIMH to develop and validate a measurement instrument to assess pediatric adherence to ART in western Kenya, and established a carefully characterized cohort of Kenyan children on ART with detailed adherence-related data. She currently has an R01 award using a cluster randomized trial to assess the effect of a patient-centered intervention guiding disclosure to HIV-infected Kenyan children and adolescents, examining clinical, virologic, adherence, emotional, and social outcomes and a supplement to develop and validate an instrument to measure HIV-related stigma as perceived and experienced by Kenyan families.

She serves as the Director of Research for the IU Center for Global Health, where her goal is to promote global healthcare systems that can implement the simple, affordable and effective interventions most needed by children and adults around the world. This network involves more than 15 insitutions, with more than $90 million in global health research funding. On the international platform, Dr. Vreeman chairs the Global Pediatric Working Group for the IeDEA consortium, which represents the world’s largest cohort of HIV-infected and exposed children.

CURRENT GRANTS

1R01MH099747-01 Vreeman (PI)
8/9/2012 - 5/31/2016
“Patient-Centered Disclosure Intervention for HIV-Infected Children”
Assessing the effect of a patient-centered intervention guiding disclosure to HIV-infected Kenyan children in a cluster-randomized trial. The primary endpoint is probability of disclosure among children, with secondary endpoints of adherence, clinical outcomes, psychological distress and social outcomes.
Role: Principal Investigator

3R01MH099747-01S1 Vreeman (PI)
12/17/2013 - 11/30/2015
“Validating an HIV-related stigma measure for families with HIV-infected children”
Supplemental R01 to develop and test a reliable, valid instrument to measure H/A stigma as perceived, enacted, and internalized by Kenyan families with HIV-infected children and adolescents.

U01 AI069911 Wools-Kaloustian (PI)
2012-2017
“International Epidemiologic Databases for the Evaluation of AIDS - IeDEA”
Epidemiologic databases of East Africa region HIV treatment programs.
Role: Co-Investigator. Plus given supplemental award for prospective pediatric adherence evaluation.


REPRESENTATIVE PUBLICATIONS

(Full List)

Vreeman RC, Nyandiko WM, Liu H, Tu W, Scanlon ML, Slaven JE, Ayaya SO, Inui TS. Measuring adherence to antiretroviral therapy in children and adolescents in western Kenya. Journal of the International AIDS Society. 2014 Nov 25;17(1):19227. doi: 10.7448/IAS.17.1.19227. eCollection 2014. PMID: 25427633

Vreeman RC, Nyandiko WM, Liu H, Tu W, Scanlon ML, Slaven JE, Ayaya SO, Inui TS. Comprehensive Evaluation of Caregiver-Reported Antiretroviral Therapy Adherence for HIV-Infected Children. AIDS and Behavior. 2015 Apr;19(4):626-34. PMID: 25613594

Vreeman RC, Wiehe SE, Ayaya SO, Musick BS, Nyandiko WM. Association of antiretroviral and clinic adherence with orphan status among HIV-infected children in western Kenya. Journal of Acquired Immune Deficiency Syndromes. 2008 Oct;49(2):163-170. PMID: 18769353

Vreeman RC, Nyandiko WM, Ayaya SO, Walumbe EG, Marrero DG, Inui TS. Factors sustaining pediatric adherence to antiretroviral therapy in Western Kenya. Qualitative Health Research 2009 19(12):1716-1729. PMID: 19949221