Medications to Maintain Cardiac Output and for Post-Resuscitation Stabilization

Medication Dose Range Comment

Inamrinone

0.75–1 mg/kg IV/IO over 5 minutes; may repeat × 2 then: 5–10 mcg/kg per minute

Inodilator

Dobutamine

2–20 mcg/kg per minute IV/IO

Inotrope; vasodilator

Dopamine

2–20 mcg/kg per minute IV/IO

Inotrope; chronotrope; renal and splanchnic vasodilator in low doses; pressor in high doses

Epinephrine

0.1–1 mcg/kg per minute IV/IO

Inotrope; chronotrope; vasodilator in low doses; pressor in higher doses

Milrinone

Loading dose: 50 mcg/kg IV/IO over 10–60 min then 0.25–0.75 mcg/kg per minute

Inodilator

Norepinephrine

0.1–2 mcg/kg per minute

Vasopressor

Sodium nitroprusside

Initial: 0.5–1 mcg/kg per minute; titrate to effect up to 8 mcg/kg per minute

Vasodilator. Prepare only in D5W

IV indicates intravenous; and IO, intraosseous.

Alternative formula for verifying dose during continuous infusion:

Infusion rate

Alternative formula for continuous infusion

Citations/References:

2015 Handbook Of Emergency Cardiovascular Care For Healthcare Providers

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