Melissa Markel, MD, MS

Melissa Markel, MD, MS

Assistant Professor of Clinical Pediatrics

Phone: 317-944-2143
Email: memarkel@iu.edu
705 Riley Hospital Drive, ROC 4340
Indianapolis, IN 46202



Pediatric Hematology Oncology

Areas of Interest

Brain tumors, solid tumors, plexiform neurofibromas.


2004 MD Penn State University College of Medicine
2007 Residency Indiana University School of Medicine
2010 Fellowship Indiana University School of Medicine
2012 MS, Clinical Research Indiana University School of Medicine

Honors & Awards

  • 2007 Red Shoes Award


Riley Outpatient Center
705 Riley Hospital Drive
Indianapolis, IN 46202
317-944-2143 phone
317-944-3107 fax

Research & Grants

A Pilot Studyof Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients with Plexiform Neurofibromas.
Funding Agency: Novartis Pharm Corp
Role: PI

Integrated approach to pathway dysregulation during vaso-occlusive crisis in sickle cell disease
Funding Agency: Indiana University Health Values Grant
Role: PI

NICHD U54: Indiana Center for Pediatric Pharmacology
Funding Agency: NIH
Role: Co-investigator

The objective of this center grant is to identify the best combinations of biomarkers to predict response to anticancer chemotherapeutic agents in children. We are carrying this out through three multidisciplinary and closely interlinked projects and two pilot projects supported by our Administrative and Biostatistics and Modeling Cores. The direct outcome of these studies will be new biomarkers and predictive signatures that will increase the precision of the existing dosing schemas used in the treatment of childhood cancer.


Monahan K., Sharpe (Markel) M., Drury D., Ertl A. and Ray C. Influence of Vestibular Activation on Respiration in Humans. Am J Physiol Regulatory Integrative Comp Physiol 282:R689-R694, 2002.

Markel M., Haut P, Renbarger J, Robertson K., Goebel W.S. Unrelated cord blood transplantation for severe congenital neutropenia: Report of two cases with very different transplant courses. Pediatr Transplant. 2008 Dec;12(8):896-901